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Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery

The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsulation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are studied because they are viewed as an important barrier to successful oral delivery. The rheological propertie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Groo, Anne-Claire, Saulnier, Patrick, Gimel, Jean-Christophe, Gravier, Julien, Ailhas, Caroline, Benoit, Jean-Pierre, Lagarce, Frederic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825687/
https://ncbi.nlm.nih.gov/pubmed/24235827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51837
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