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Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery

The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsulation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are studied because they are viewed as an important barrier to successful oral delivery. The rheological propertie...

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Bibliografiske detaljer
Main Authors: Groo, Anne-Claire, Saulnier, Patrick, Gimel, Jean-Christophe, Gravier, Julien, Ailhas, Caroline, Benoit, Jean-Pierre, Lagarce, Frederic
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825687/
https://ncbi.nlm.nih.gov/pubmed/24235827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51837
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