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Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling

ABSTRACT: Renal fibrosis is a common consequence of unilateral ureteral obstruction, which provides a useful model to investigate the pathogenesis of obstructive nephropathy and progressive renal fibrosis. Transforming growth factor (TGF-β1) has been recognized as a key mediator in renal fibrosis by...

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Detalhes bibliográficos
Main Authors: Park, Jinah, Lee, So-Young, Ooshima, Akira, Yang, Kyung-Min, Kang, Jin Muk, Kim, Young-Woong, Kim, Seong-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825548/
https://ncbi.nlm.nih.gov/pubmed/24072041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1086-1
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