Chemotherapy With Erlotinib or Chemotherapy Alone in Advanced Non-Small Cell Lung Cancer With Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

PURPOSE. Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer has an oncogene-addicted biology that confers sensitivity to EGFR tyrosine kinase inhibitors (TKIs). Published data suggest that EGFR addiction persists after development of TKI acquired resistance, leading many clini...

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Hlavní autoři: Goldberg, Sarah B., Oxnard, Geoffrey R., Digumarthy, Subba, Muzikansky, Alona, Jackman, David M., Lennes, Inga T., Sequist, Lecia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2013
Témata:
Lung Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825307/
https://ncbi.nlm.nih.gov/pubmed/24072220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0168
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