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Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins
Prions are unconventional infectious agents that are composed of misfolded aggregated prion protein. Prions replicate their conformation by template-assisted conversion of the endogenous prion protein PrP. Templated conversion of soluble proteins into protein aggregates is also a hallmark of other n...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Publishing Corporation
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825132/ https://ncbi.nlm.nih.gov/pubmed/24282413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/704546 |
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