HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1

HIV-1 glycoprotein 120 (gp120) is known to cause neurotoxicity via several mechanisms including production of proinflammatory cytokines/chemokines and oxidative stress. Likewise, drug abuse is thought to have a direct impact on the pathology of HIV-associated neuroinflammation through the induction...

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Bibliografiske detaljer
Main Authors: Shah, A, Kumar, S, Simon, S D, Singh, D P, Kumar, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824683/
https://ncbi.nlm.nih.gov/pubmed/24113184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.374
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