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A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance

The emergence of drug resistant tumours that are able to escape cell death pose a major problem in the treatment of cancers. Tumours develop resistance to DNA-damaging chemotherapeutic agents by acquiring the ability to repair their DNA. Combination therapies that induce DNA damage and disrupt the D...

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Main Authors: Wansleben, S, Davis, E, Peres, J, Prince, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824674/
https://ncbi.nlm.nih.gov/pubmed/24113180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.365
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