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Activation and Proton Transport Mechanism in Influenza A M2 Channel

Molecular dynamics trajectories 2 μs in length have been generated for the pH-activated, tetrameric M2 proton channel of the influenza A virus in all protonation states of the pH sensor located at the His(37) tetrad. All simulated structures are in very good agreement with high-resolution structures...

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Detalhes bibliográficos
Main Authors: Wei, Chenyu, Pohorille, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824548/
https://ncbi.nlm.nih.gov/pubmed/24209848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.030
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