Selective anticancer agents suppress aging in Drosophila

Mutations of the PI3K, TOR, iNOS, and NF-κB genes increase lifespan of model organisms and reduce the risk of some aging-associated diseases. We studied the effects of inhibitors of PI3K (wortmannin), TOR (rapamycin), iNOS (1400W), NF-κB (pyrrolidin dithiocarbamate and QNZ), and the combined effects...

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Main Authors: Danilov, Anton, Shaposhnikov, Mikhail, Plyusnina, Ekaterina, Kogan, Valeria, Fedichev, Peter, Moskalev, Alexey
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2013
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Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824538/
https://ncbi.nlm.nih.gov/pubmed/24096697
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