A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63

A compromised Fanconi Anemia (FA) signaling pathway, often resulting from an inactivated FANCD2, was recently recognized to contribute to the development of non-FA human tumors. However, it is largely unknown as to how an impaired FA pathway or an inactivated FANCD2 promotes tumorigenesis. Here we u...

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Autors principals: Panneerselvam, Jayabal, Pickering, Anna, Zhang, Jun, Wang, Hong, Tian, Hui, Zheng, Junnian, Fei, Peiwen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824532/
https://ncbi.nlm.nih.gov/pubmed/23965832
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