Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage

How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fu, Dechen, Dudimah, Fred Duafalia, Zhang, Jun, Pickering, Anna, Paneerselvam, Jayabal, Palrasu, Manikandan, Wang, Hong, Fei, Peiwen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610727/
https://ncbi.nlm.nih.gov/pubmed/23388460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23755
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