Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage

How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA d...

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Bibliographische Detailangaben
Hauptverfasser: Fu, Dechen, Dudimah, Fred Duafalia, Zhang, Jun, Pickering, Anna, Paneerselvam, Jayabal, Palrasu, Manikandan, Wang, Hong, Fei, Peiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610727/
https://ncbi.nlm.nih.gov/pubmed/23388460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23755
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