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Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage

How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA d...

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主要な著者: Fu, Dechen, Dudimah, Fred Duafalia, Zhang, Jun, Pickering, Anna, Paneerselvam, Jayabal, Palrasu, Manikandan, Wang, Hong, Fei, Peiwen
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610727/
https://ncbi.nlm.nih.gov/pubmed/23388460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23755
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