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Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer

Transcriptional regulation of miRNAs that control the pathogenesis of breast cancer remains largely unknown. Here, we showed that ionizing radiation, a known breast carcinogen, triggered the differential expression of miR-20b in mammary tissues. We identified several GC-rich consensus binding motifs...

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Detalhes bibliográficos
Main Authors: Li, Dongping, Ilnytskyy, Yaroslav, Kovalchuk, Anna, Khachigian, Levon M., Bronson, Roderick T., Wang, Bo, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824527/
https://ncbi.nlm.nih.gov/pubmed/23945289
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