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Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression()

BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...

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Hlavní autoři: Groselj, Blaz, Kerr, Martin, Kiltie, Anne E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Scientific Publishers 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824066/
https://ncbi.nlm.nih.gov/pubmed/23932191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2013.06.021
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