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γ-Hydroxybutyric Acid (GHB) Is Not an Agonist of Extrasynaptic GABA(A) Receptors

γ-Hydroxybutyric acid (GHB) is an endogenous compound and a drug used clinically to treat the symptoms of narcolepsy. GHB is known to be an agonist of GABA(B) receptors with millimolar affinity, but also binds with much higher affinity to another site, known as the GHB receptor. While a body of evid...

詳細記述

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書誌詳細
主要な著者: Connelly, William M., Errington, Adam C., Crunelli, Vincenzo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823990/
https://ncbi.nlm.nih.gov/pubmed/24244421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079062
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