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γ-Hydroxybutyric Acid (GHB) Is Not an Agonist of Extrasynaptic GABA(A) Receptors

γ-Hydroxybutyric acid (GHB) is an endogenous compound and a drug used clinically to treat the symptoms of narcolepsy. GHB is known to be an agonist of GABA(B) receptors with millimolar affinity, but also binds with much higher affinity to another site, known as the GHB receptor. While a body of evid...

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Bibliografiset tiedot
Päätekijät: Connelly, William M., Errington, Adam C., Crunelli, Vincenzo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823990/
https://ncbi.nlm.nih.gov/pubmed/24244421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079062
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