Comparison of the repair of potentially lethal damage after low- and high-LET radiation exposure, assessed from the kinetics and fidelity of chromosome rejoining in normal human fibroblasts

Potentially lethal damage (PLD) and its repair (PLDR) were studied in confluent human fibroblasts by analyzing the kinetics of chromosome break rejoining after X-ray or heavy-ion exposures. Cells were either held in the non-cycling G(0) phase of the cell cycle for 12 h, or forced to proliferate imme...

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Hlavní autoři: Liu, Cuihua, Kawata, Tetsuya, Zhou, Guangming, Furusawa, Yoshiya, Kota, Ryuichi, Kumabe, Atsuhiro, Sutani, Shinya, Fukada, Junichi, Mishima, Masayo, Shigematsu, Naoyuki, George, Kerry, Cucinotta, Francis
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823769/
https://ncbi.nlm.nih.gov/pubmed/23674607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrt031
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