Comparison of the repair of potentially lethal damage after low- and high-LET radiation exposure, assessed from the kinetics and fidelity of chromosome rejoining in normal human fibroblasts

Potentially lethal damage (PLD) and its repair (PLDR) were studied in confluent human fibroblasts by analyzing the kinetics of chromosome break rejoining after X-ray or heavy-ion exposures. Cells were either held in the non-cycling G(0) phase of the cell cycle for 12 h, or forced to proliferate imme...

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Detalhes bibliográficos
Main Authors: Liu, Cuihua, Kawata, Tetsuya, Zhou, Guangming, Furusawa, Yoshiya, Kota, Ryuichi, Kumabe, Atsuhiro, Sutani, Shinya, Fukada, Junichi, Mishima, Masayo, Shigematsu, Naoyuki, George, Kerry, Cucinotta, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823769/
https://ncbi.nlm.nih.gov/pubmed/23674607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrt031
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