High-Mobility Group Box 1 Inhibits Gastric Ulcer Healing through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products

High-mobility group box 1 (HMGB1) was initially discovered as a nuclear protein that interacts with DNA as a chromatin-associated non-histone protein to stabilize nucleosomes and to regulate the transcription of many genes in the nucleus. Once leaked or actively secreted into the extracellular envir...

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Hauptverfasser: Nadatani, Yuji, Watanabe, Toshio, Tanigawa, Tetsuya, Ohkawa, Fumikazu, Takeda, Shogo, Higashimori, Akira, Sogawa, Mitsue, Yamagami, Hirokazu, Shiba, Masatsugu, Watanabe, Kenji, Tominaga, Kazunari, Fujiwara, Yasuhiro, Takeuchi, Koji, Arakawa, Tetsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823709/
https://ncbi.nlm.nih.gov/pubmed/24244627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080130
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