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THE INSULIN RECEPTOR TRANSLOCATES TO THE NUCLEUS TO REGULATE CELL PROLIFERATION IN LIVER
Insulin’s metabolic effects in the liver are widely appreciated, but insulin’s ability to act as a hepatic mitogen is less well understood. Because the Insulin Receptor (IR) can traffic to the nucleus, and calcium (Ca(2+)) signals within the nucleus regulate cell proliferation, we investigated wheth...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823683/ https://ncbi.nlm.nih.gov/pubmed/23839970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26609 |
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