The Synergistic Effect of Everolimus and Chloroquine on Endothelial Cell Number Reduction Is Paralleled by Increased Apoptosis and Reduced Autophagy Occurrence

Endothelial Progenitor Cells (EPCs), a minor subpopulation of the mononuclear cell fraction in peripheral blood, play a critical role in cancer development as they contribute to angiogenesis-mediated pathological neovascularization. In response to tumor cytokines, including VEGF, EPCs mobilize from...

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Détails bibliographiques
Auteurs principaux: Grimaldi, Anna, Balestrieri, Maria Luisa, D'Onofrio, Nunzia, Di Domenico, Gilda, Nocera, Cosimo, Lamberti, Monica, Tonini, Giuseppe, Zoccoli, Alice, Santini, Daniele, Caraglia, Michele, Pantano, Francesco
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823580/
https://ncbi.nlm.nih.gov/pubmed/24244540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079658
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