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Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease

Growth/differentiation factor 5 (GDF5) is a neurotrophic factor that promotes the survival of midbrain dopaminergic neurons in vitro and in vivo and as such is potentially useful in the treatment of Parkinson's disease (PD). This study shows that a continuous supply of GDF5, produced by transpl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costello, Daniel J, O'Keeffe, Gerard W, Hurley, Fiona M, Sullivan, Aideen M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823439/
https://ncbi.nlm.nih.gov/pubmed/22436046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01562.x
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