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Crystal Structures of Substrate-Free and Nitrosyl Cytochrome P450cin: Implications for O(2) Activation

The crystal structure of the P450cin substrate-bound nitric oxide complex and the substrate-free form have been determined revealing a substrate-free structure that adopts an open conformation relative to the substrate-bound structure. The region of the I helix that forms part of the O(2) binding po...

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Detalhes bibliográficos
Main Authors: Madrona, Yarrow, Tripathi, Sarvind, Li, Huiying, Poulos, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823376/
https://ncbi.nlm.nih.gov/pubmed/22775403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300666u
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