A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling

Platinum anticancer drugs have been used for three decades despite their serious side effects and the emerging of resistance phenomena. Recently, a phosphine copper(I) complex, [Cu(thp)(4)][PF(6)] (CP), gained special attention because of its strong antiproliferative effects. CP killed human colon c...

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Detalhes bibliográficos
Main Authors: Gandin, Valentina, Pellei, Maura, Tisato, Francesco, Porchia, Marina, Santini, Carlo, Marzano, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823100/
https://ncbi.nlm.nih.gov/pubmed/21388518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01292.x
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