TNFα blockade prevents the development of inflammatory bowel disease in HLA-B27 transgenic rats

Rats transgenic for HLA-B27 and human β2microglobulin (B27TR) develop a multi-systemic disease resembling inflammatory bowel disease (IBD) and spondyloarthritis. TNFα has a crucial role in chronic inflammation. Our objective was to evaluate the effect of anti-TNFα treatment on spontaneous IBD in B27...

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Bibliografiske detaljer
Main Authors: Milia, Anna Franca, Manetti, Mirko, Generini, Sergio, Polidori, Lucia, Benelli, Gemma, Cinelli, Marina, Messerini, Luca, Ibba-Manneschi, Lidia, Matucci-Cerinic, Marco
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823044/
https://ncbi.nlm.nih.gov/pubmed/18363845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00310.x
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