Evidence for the prevention of enthesitis in HLA-B27/hβ(2)m transgenic rats treated with a monoclonal antibody against TNF-α

Transgenic rats with high expression of HLA-B27 and human β(2)-microglobulin (B27TR) develop a multisystem inflammatory disease resembling human inflammatory bowel disease (IBD) and spondyloarthropaties (SpA). Tumour necrosis factor α (TNF-α) has a crucial role in sustaining chronic inflammation in...

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Main Authors: Milia, Anna Franca, Ibba-Manneschi, Lidia, Manetti, Mirko, Benelli, Gemma, Generini, Sergio, Messerini, Luca, Matucci-Cerinic, Marco
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822794/
https://ncbi.nlm.nih.gov/pubmed/20015205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00984.x
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