Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells

Triple-negative breast cancers (TNBCs) are known to be intrinsically resistant to inhibitors for epidermal growth factor receptor (EGFR). Until now, clinical trials for TNBCs using EGFR inhibitors (EGFRis) as single agents have yielded disappointing results. Here, we report that combinatorial treatm...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yi, Yong Weon, Hong, Wooyoung, Kang, Hyo Jin, Kim, Hee Jeong, Zhao, Wenjing, Wang, Antai, Seong, Yeon-Sun, Bae, Insoo
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2013
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822817/
https://ncbi.nlm.nih.gov/pubmed/23601074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12046
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