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Calcineurin A-β is required for hypertrophy but not matrix expansion in the diabetic kidney
Calcineurin is an important signalling protein that regulates a number of molecular and cellular processes. Previously, we found that inhibition of calcineurin with cyclosporine reduced renal hypertrophy and blocked glomerular matrix expansion in the diabetic kidney. Isoforms of the catalytic subuni...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822805/ https://ncbi.nlm.nih.gov/pubmed/19778355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00910.x |
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