Analysis of microdissected neurons by (18)O mass spectrometry reveals altered protein expression in Alzheimer's disease

It is evident that the symptoms of Alzheimer's disease (AD) are derived from severe neuronal damage, and especially pyramidal neurons in the hippocampus are affected pathologically. Here, we analysed the proteome of hippocampal neurons, isolated from post-mortem brains by laser capture microdis...

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Autors principals: Hashimoto, Masakazu, Bogdanovic, Nenad, Nakagawa, Hiroyuki, Volkmann, Inga, Aoki, Mikio, Winblad, Bengt, Sakai, Jun, Tjernberg, Lars O
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822682/
https://ncbi.nlm.nih.gov/pubmed/21883897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01441.x
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