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Interleukin-1 induces pro-inflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium

In the infarcted myocardium, activation of the inflammatory cascade clears the wound from dead cells, while stimulating matrix degradation and chamber dilation, thus contributing to the development of heart failure. IL-1 is critically involved in the post-infarction inflammatory reaction and mediate...

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Autori principali: Saxena, Amit, Chen, Wei, Su, Ya, Rai, Vikrant, Uche, Olisambu U, Li, Na, Frangogiannis, Nikolaos G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822582/
https://ncbi.nlm.nih.gov/pubmed/24078695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300725
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