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Interleukin-1 induces pro-inflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium

In the infarcted myocardium, activation of the inflammatory cascade clears the wound from dead cells, while stimulating matrix degradation and chamber dilation, thus contributing to the development of heart failure. IL-1 is critically involved in the post-infarction inflammatory reaction and mediate...

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Detalhes bibliográficos
Main Authors: Saxena, Amit, Chen, Wei, Su, Ya, Rai, Vikrant, Uche, Olisambu U, Li, Na, Frangogiannis, Nikolaos G
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822582/
https://ncbi.nlm.nih.gov/pubmed/24078695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300725
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