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Interleukin-1 induces pro-inflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium

In the infarcted myocardium, activation of the inflammatory cascade clears the wound from dead cells, while stimulating matrix degradation and chamber dilation, thus contributing to the development of heart failure. IL-1 is critically involved in the post-infarction inflammatory reaction and mediate...

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Bibliografiska uppgifter
Huvudupphovsmän: Saxena, Amit, Chen, Wei, Su, Ya, Rai, Vikrant, Uche, Olisambu U, Li, Na, Frangogiannis, Nikolaos G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822582/
https://ncbi.nlm.nih.gov/pubmed/24078695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300725
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