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Rational design of FRET sensor proteins based on mutually exclusive domain interactions

Proteins that switch between distinct conformational states are ideal to monitor and control molecular processes within the complexity of biological systems. Inspired by the modular architecture of natural signaling proteins, our group explores generic design strategies for the construction of FRET-...

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Autors principals: Merkx, Maarten, Golynskiy, Misha V., Lindenburg, Laurens H., Vinkenborg, Jan L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822149/
https://ncbi.nlm.nih.gov/pubmed/24059509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130128
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