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MagFRET: The First Genetically Encoded Fluorescent Mg(2+) Sensor

Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor is based on the high-affinity Mg(2+) binding doma...

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Detalhes bibliográficos
Main Authors: Lindenburg, Laurens H., Vinkenborg, Jan L., Oortwijn, Jorn, Aper, Stijn J. A., Merkx, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846734/
https://ncbi.nlm.nih.gov/pubmed/24312622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082009
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