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B7 family checkpoint regulators in immune regulation and disease
Fine-tuning the immune response and maintaining tolerance to self antigens involves a complex network of co-stimulatory and co-inhibitory molecules. The recent FDA approval of ipilimumab, a monoclonal antibody blocking CTLA-4, demonstrates the impact of checkpoint regulators in disease. This is rein...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3821798/ https://ncbi.nlm.nih.gov/pubmed/23954143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.07.003 |
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