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B7 family checkpoint regulators in immune regulation and disease

Fine-tuning the immune response and maintaining tolerance to self antigens involves a complex network of co-stimulatory and co-inhibitory molecules. The recent FDA approval of ipilimumab, a monoclonal antibody blocking CTLA-4, demonstrates the impact of checkpoint regulators in disease. This is rein...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ceeraz, Sabrina, Nowak, Elizabeth C, Noelle, Randolph J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821798/
https://ncbi.nlm.nih.gov/pubmed/23954143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.07.003
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