CO(2) directly modulates connexin 26 by formation of carbamate bridges between subunits

Homeostatic regulation of the partial pressure of CO(2) (PCO(2)) is vital for life. Sensing of pH has been proposed as a sufficient proxy for determination of PCO(2) and direct CO(2)-sensing largely discounted. Here we show that connexin 26 (Cx26) hemichannels, causally linked to respiratory chemose...

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Autori principali: Meigh, Louise, Greenhalgh, Sophie A, Rodgers, Thomas L, Cann, Martin J, Roper, David I, Dale, Nicholas
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2013
Soggetti:
Biophysics and Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821526/
https://ncbi.nlm.nih.gov/pubmed/24220509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01213
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