CO(2) directly modulates connexin 26 by formation of carbamate bridges between subunits

Homeostatic regulation of the partial pressure of CO(2) (PCO(2)) is vital for life. Sensing of pH has been proposed as a sufficient proxy for determination of PCO(2) and direct CO(2)-sensing largely discounted. Here we show that connexin 26 (Cx26) hemichannels, causally linked to respiratory chemose...

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Hauptverfasser: Meigh, Louise, Greenhalgh, Sophie A, Rodgers, Thomas L, Cann, Martin J, Roper, David I, Dale, Nicholas
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2013
Schlagworte:
Biophysics and Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821526/
https://ncbi.nlm.nih.gov/pubmed/24220509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01213
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