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CO(2) directly modulates connexin 26 by formation of carbamate bridges between subunits

Homeostatic regulation of the partial pressure of CO(2) (PCO(2)) is vital for life. Sensing of pH has been proposed as a sufficient proxy for determination of PCO(2) and direct CO(2)-sensing largely discounted. Here we show that connexin 26 (Cx26) hemichannels, causally linked to respiratory chemose...

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Detalhes bibliográficos
Main Authors: Meigh, Louise, Greenhalgh, Sophie A, Rodgers, Thomas L, Cann, Martin J, Roper, David I, Dale, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821526/
https://ncbi.nlm.nih.gov/pubmed/24220509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01213
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