Targeting nucleic acid secondary structures by antisense oligonucleotides designed through in vitro selection.
Using an in vitro selection approach, we have isolated oligonucleotides that can bind to a DNA hairpin structure. Complex formation of these oligonucleotides with the target hairpin involves some type of triple-stranded structure with noncanonical interaction, as indicated by bandshift assays and fo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10679 |
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