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HLA ligandome tumor antigen discovery for personalized vaccine approach

Every cancer is different and cancer cells differ from normal cells, in particular, through genetic alterations. HLA molecules on the cell surface enable T lymphocytes to recognize cellular alterations as antigens, including mutations, increase in gene product copy numbers or expression of genes usu...

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Detalhes bibliográficos
Main Authors: Rammensee, Hans-Georg, Singh-Jasuja, Harpreet
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821395/
https://ncbi.nlm.nih.gov/pubmed/24090147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2013.836911
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