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HLA ligandome tumor antigen discovery for personalized vaccine approach

Every cancer is different and cancer cells differ from normal cells, in particular, through genetic alterations. HLA molecules on the cell surface enable T lymphocytes to recognize cellular alterations as antigens, including mutations, increase in gene product copy numbers or expression of genes usu...

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Autors principals: Rammensee, Hans-Georg, Singh-Jasuja, Harpreet
Format: Artigo
Idioma:Inglês
Publicat: Informa Healthcare 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821395/
https://ncbi.nlm.nih.gov/pubmed/24090147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2013.836911
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