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Role of Conformational Entropy in the Activity and Regulation of the catalytic subunit of Protein Kinase A

Protein kinase A (PKA) is the archetypical phosphokinase, sharing a catalytic core with the entire protein kinase superfamily. In eukaryotes, the ubiquitous location of PKA makes it one of the most important cellular signaling molecules, involved in a myriad of events. The catalytic-subunit of PKA (...

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Autores principales: Veglia, Gianluigi, Cembran, Alessandro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821181/
https://ncbi.nlm.nih.gov/pubmed/23902454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12462
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