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Preferential apelin-13 production by the proprotein convertase PCSK3 is implicated in obesity()
The peptide hormone apelin is translated as a 77-residue preproprotein, truncated to the 55-residue proapelin and, subsequently, to 13–36-residue bioactive isoforms named apelin-13 to -36. Proapelin is hypothesized to be cleaved to apelin-36 and then to the shorter isoforms. However, neither the mec...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3821026/ https://ncbi.nlm.nih.gov/pubmed/24251091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.08.001 |
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