Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes

PRIMARY OBJECTIVE: Heparin-binding EGF-like growth factor (HB-EGF) protects the intestine from damage in animals. Future clinical trials of HB-EGF may involve administration of repeated doses of HB-EGF. Since HB-EGF activates EGF receptors which have been implicated in tumor development, we examined...

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Main Authors: CHEN, CHUN-LIANG, MEHTA, VEELA B., ZHANG, HONG-YI, WU, DANA, OTABOR, IYORE, RADULESCU, ANDREI, EL-ASSAL, OSAMA N., FENG, JIEXIONG, CHEN, YAN, BESNER, GAIL E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821006/
https://ncbi.nlm.nih.gov/pubmed/19939201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977190903407365
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