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Stabilization of Speckle-type POZ Protein (Spop) by Daz Interacting Protein 1 (Dzip1) Is Essential for Gli Turnover and the Proper Output of Hedgehog Signaling

The Hedgehog (Hh) pathway is essential for embryonic development and adult tissue homeostasis. The Gli/Cubitus interruptus (Ci) family of transcription factors acts at the downstream end of the pathway to mediate Hh signaling. Both Hh-dependent and -independent Gli regulatory mechanisms are importan...

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מידע ביבליוגרפי
Main Authors: Schwend, Tyler, Jin, Zhigang, Jiang, Kai, Mitchell, Brian J., Jia, Jianhang, Yang, Jing
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820914/
https://ncbi.nlm.nih.gov/pubmed/24072710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512962
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