A Nondiscriminating Glutamyl-tRNA Synthetase in the Plasmodium Apicoplast: THE FIRST ENZYME IN AN INDIRECT AMINOACYLATION PATHWAY

The malaria parasite Plasmodium falciparum and related organisms possess a relict plastid known as the apicoplast. Apicoplast protein synthesis is a validated drug target in malaria because antibiotics that inhibit translation in prokaryotes also inhibit apicoplast protein synthesis and are sometime...

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Detalhes bibliográficos
Main Authors: Mailu, Boniface M., Ramasamay, Gowthaman, Mudeppa, Devaraja G., Li, Ling, Lindner, Scott E., Peterson, Megan J., DeRocher, Amy E., Kappe, Stefan H. I., Rathod, Pradipsinh K., Gardner, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820887/
https://ncbi.nlm.nih.gov/pubmed/24072705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507467
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