Structural Basis and Targeting of the Interaction between Fibroblast Growth Factor-inducible 14 and Tumor Necrosis Factor-like Weak Inducer of Apoptosis

Deregulation of the TNF-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling pathway is observed in many diseases, including inflammation, autoimmune diseases, and cancer. Activation of Fn14 signaling by TWEAK binding triggers cell invasion and survival and t...

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Detalhes bibliográficos
Main Authors: Dhruv, Harshil, Loftus, Joseph C., Narang, Pooja, Petit, Joachim L., Fameree, Maureen, Burton, Julien, Tchegho, Giresse, Chow, Donald, Yin, Holly, Al-Abed, Yousef, Berens, Michael E., Tran, Nhan L., Meurice, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820864/
https://ncbi.nlm.nih.gov/pubmed/24056367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493536
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