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Developmental reprogramming of cancer susceptibility

Gene–environment interactions have been traditionally understood to promote the acquisition of mutations that drive multistage carcinogenesis, and, in the case of inherited defects in tumour suppressor genes, additional mutations are required for cancer development. However, the developmental origin...

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Detalles Bibliográficos
Main Authors: Walker, Cheryl Lyn, Ho, Shuk-mei
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820510/
https://ncbi.nlm.nih.gov/pubmed/22695395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3220
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