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Developmental reprogramming of cancer susceptibility

Gene–environment interactions have been traditionally understood to promote the acquisition of mutations that drive multistage carcinogenesis, and, in the case of inherited defects in tumour suppressor genes, additional mutations are required for cancer development. However, the developmental origin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Walker, Cheryl Lyn, Ho, Shuk-mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820510/
https://ncbi.nlm.nih.gov/pubmed/22695395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3220
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