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Developmental reprogramming of cancer susceptibility
Gene–environment interactions have been traditionally understood to promote the acquisition of mutations that drive multistage carcinogenesis, and, in the case of inherited defects in tumour suppressor genes, additional mutations are required for cancer development. However, the developmental origin...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820510/ https://ncbi.nlm.nih.gov/pubmed/22695395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3220 |
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