An IgE receptor mimetic peptide (PepE) protects mice from IgE mediated anaphylaxis

Crosslinking of receptor-bound Immunoglobulin E (IgE) triggers immediate hypersensitivity reactions including anaphylaxis. Blocking the interaction of IgE with its high-affinity receptor, FcεRI, on mast cells and basophils is an attractive strategy for the treatment of allergies. This approach has s...

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Bibliographic Details
Main Authors: Zhou, Joseph S, Sandomenico, Annamaria, Severino, Valeria, Burton, Oliver T, Darling, Alanna, Oettgen, Hans C, Ruvo, Menotti
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820499/
https://ncbi.nlm.nih.gov/pubmed/24056872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb70286c
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