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The Role of Tau in Neurodegenerative Diseases and Its Potential as a Therapeutic Target

The abnormal deposition of proteins in and around neurons is a common pathological feature of many neurodegenerative diseases. Among these pathological proteins, the microtubule-associated protein tau forms intraneuronal filaments in a spectrum of neurological disorders. The discovery that dominant...

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Bibliographic Details
Main Author: Wolfe, Michael S.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820460/
https://ncbi.nlm.nih.gov/pubmed/24278740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6064/2012/796024
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