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Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice

Lipid disorders pose therapeutic challenges. Previously we discovered that mutation of the hepatocyte β-hydroxybutyrate transporter Slc16a6a in zebrafish causes hepatic steatosis during fasting, marked by increased hepatic triacylglycerol, but not cholesterol. This selective diversion of trapped ket...

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Detalhes bibliográficos
Main Authors: Karanth, Santhosh, Tran, Vy My, Kuberan, Balagurunathan, Schlegel, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820260/
https://ncbi.nlm.nih.gov/pubmed/24057001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013425
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