Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.

Inactivation of the von Hippel-Lindau protein (pVHL) has been implicated in the pathogenesis of renal carcinomas and central nervous system hemangioblastomas. These are highly vascular tumors which overproduce angiogenic peptides such as vascular endothelial growth factor/vascular permeability facto...

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Bibliografiske detaljer
Main Authors: Iliopoulos, O, Levy, A P, Jiang, C, Kaelin, W G, Goldberg, M A
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38198/
https://ncbi.nlm.nih.gov/pubmed/8855223
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