Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.

Inactivation of the von Hippel-Lindau protein (pVHL) has been implicated in the pathogenesis of renal carcinomas and central nervous system hemangioblastomas. These are highly vascular tumors which overproduce angiogenic peptides such as vascular endothelial growth factor/vascular permeability facto...

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Detalhes bibliográficos
Main Authors: Iliopoulos, O, Levy, A P, Jiang, C, Kaelin, W G, Goldberg, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38198/
https://ncbi.nlm.nih.gov/pubmed/8855223
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