Targeted Radiosensitization of ETS Fusion-Positive Prostate Cancer through PARP1 Inhibition

ETS gene fusions, which result in overexpression of an ETS transcription factor, are considered driving mutations in approximately half of all prostate cancers. Dysregulation of ETS transcription factors is also known to exist in Ewing's sarcoma, breast cancer, and acute lymphoblastic leukemia....

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Detalhes bibliográficos
Main Authors: Han, Sumin, Brenner, J Chad, Sabolch, Aaron, Jackson, Will, Speers, Corey, Wilder-Romans, Kari, Knudsen, Karen E, Lawrence, Theodore S, Chinnaiyan, Arul M, Feng, Felix Y
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819636/
https://ncbi.nlm.nih.gov/pubmed/24204199
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